4-Hydroxy-3-nitro-5-pyridinecarboxylic acid

4-Hydroxy-3-nitro-5-pyridinecarboxylic acid - Names and Identifiers

Name	4-hydroxy-5-nitropyridine-3-carboxylic acid
Synonyms	4-Hydroxy-5-nitronicotinic acid 4-hydroxy-5-nitropyridine-3-carboxylic acid 4-Hydroxy-5-nitropyridine-3-carboxylic acid 4-Hydroxy-3-nitro-5-pyridinecarboxylic acid 3-Pyridinecarboxylic acid, 4-hydroxy-5-nitro- 3-pyridinecarboxylic acid, 4-hydroxy-5-nitro-
CAS	911461-03-5
InChI	InChI=1/C6H4N2O5/c9-5-3(6(10)11)1-7-2-4(5)8(12)13/h1-2H,(H,7,9)(H,10,11)

4-Hydroxy-3-nitro-5-pyridinecarboxylic acid - Physico-chemical Properties

Molecular Formula	C6H4N2O5
Molar Mass	184.11
Density	1.745±0.06 g/cm3(Predicted)
Melting Point	217-219 °C(Solv: ethanol (64-17-5))
Boling Point	478.1±45.0 °C(Predicted)
Flash Point	242.952°C
Vapor Presure	0mmHg at 25°C
pKa	-1.62±0.21(Predicted)
Storage Condition	2-8°C
Refractive Index	1.677

4-Hydroxy-3-nitro-5-pyridinecarboxylic acid - Introduction

Acid is an organic compound with the chemical formula C6H4N2O5.

The compound is a yellow crystalline solid with a bitter taste. It is slightly soluble in water and can be dissolved under acidic conditions. The compound has a double bond architecture and substituents and therefore has a particular reactivity in chemical reactions.

Acid has a wide range of uses in the fields of pharmaceuticals, dyes and chemical reagents. It can be used as an important intermediate in the synthesis of antibiotic drugs, dyes and pigments, and organic synthesis.

Preparation of β-acid can be obtained by reacting 3-amino-4-hydroxypyridine with a nitrating reagent. 3-Amino-4-hydroxypyridine is first reacted with a nitrating reagent, such as a mixture of concentrated sulfuric acid and nitric acid, to give an intermediate product. Then hydrolysis or oxidation reaction is carried out to obtain the final product acid.

In terms of safety, acid is a toxic compound that is irritating. Personal protective equipment such as protective gloves and goggles should be worn when exposed to this compound. At the same time, it should be operated in a well-ventilated place to avoid inhaling its dust, gas or vapor. If you accidentally touch or eat, you should seek medical attention in time.

Last Update：2024-04-09 21:11:58